Hypodermic injection apparatus, and method of preparing for and making such injections



, April 15, 1941. C. c. DICKINSON ETAL l 2,238,582

HYPODERMIC INJECTION APPARATUS, AND METHOD 0F PREPARING FOR AND MAKING SUCH INJECTIONS Filed April 21. 19:53

v I NVE NTOR.

UNiTEof--STATES infirslyr OFFICE.

HYPODERMIC INJECTION APPARATUS, AND

METHOD OF PREPARING FOR AND MAK- ING SUCH INJECTIONS l Cloyd C. Dickinson and Clayton F. B. Stowell, Chicago, lll., assignors, by direct and mesne assignmcnts, to Frank C.- McCrnm, Chicago, Ill.

Application April 21, 193s, serial no. 607,236

s claims. (ci. 12s-21e) Our invention relates to means for effecting convenient and sterile hypodermic injections, and

yto accomplish the desired result we utilize the well known and commonly used syringe conement. such as novocaine may be isolated from 1 the carrier or diluent untily actually ready for use;

A further object is to provide suitable means for accomplishing thisresult and so arrangingv the parts that lt will be impossible for a user to make an error in theact of loading and operating the syringe.

The invention will be more readily understood by reference to the accompanying drawing, in

Fig. l is a side elevation of a conventional syringe into which the cartridge of our invention has been loaded. the view showing the'syringe partly emptied by action of the plunger on the plug closure for the cartridge;

Fig. 2 is a view somewhat enlarged of the cartridge of' our invention;

Fig. 3 is an enlarged sectional view o f one end ofthe cartridge;v 1 v Fig. 4 is a sectional view of the assembly of the cartridge and syringe at the lower end showing the action following the placing of the cartridge in position, and

Fig. 5 is a composite perspective view oi' the plug, sleeve and closure foithe lower end of the cartridge.

In the drawing in Fig. l we have` shown a conventional form of syringe in which the upper end is adapted to be swung out of line with the cylindrical body portion or barrel II in order to present an open end of the barrel for reception of the cartridge. The cartridge consists of a, tube t, preferably composed oi' glass, and of uniform diameter `from end to end. The lower or left hand end as viewed in Fig. 2 is closed by means of a plug I having a flange 2 that serves to limit4 the entrance of the plug into the tube. The plug has a chamber or recess I axially arranged therein and within this chamber we have shown a small cylinder l normally open at both ends Vand used merely to stien the walls of the plug or stopper. Of course, it is obvious that the cylinder 8 may be omitted if desired, the chamber within the plug constituting the container for the drug. In the drawing we have shown the outer end of the cylindrical member l as closed by a disc 4 which will preferably be of a material that will not be readily punctured by the inwardly projecting end of the hypodermicl needle. The disc will be sealed in place by suitable means. A carrier or diluent for the medicament is contained within the closed tube, as indicated at 1, the medicament within the chamber in the plug being indicated at I0.

At its opposite end the cartridge i-s closed by means of an unilanged plug l2 that acts as a piston when displaced by the thrust of the plunger I3 of the syringe.

It being understood that the hypodermic needle H is firmly held in the position shown in the drawing with its inner end i5 projecting injto the space within the syringe cylinder or barrel. To load the syringe, the upper end is swung to open the barrel, whereupon the cartridge is placed in the barrel and pushed downward. As a result of this manipulation, the inwardly projecting end i5 of the needle is forced through the non-metallic plug l, thence through the chamber land into contact with the hard disc 4, breaking the seal and displacing the disc, as best shown in Fig. 4. Inasmuch as the opening in the chamber that is closed by the disc 4 is the'full size of the chamber and as the closure will be entirely removed from the adjacent space, the two materials-th`at is the medicament I0 and the carrier l-wiil immediately enter into a mixture. Thereafter the upper end of the syringe is swung into closed position; and it will be noted that it cannot be swung into that positionunless the cartridge is pushed all the way in; in other Words', the syringe cannot be closed untilthe ness of th'emixture,v complete sterility of the.

syrlnge and'certainty voi' combination or mixture of the two chemicals'before any discharge from the cartridgecan be effected.

Obvious the construction is capable of some modifications and we do not wish to be limited except as indicated in the appended claims.

We claim:

1. In combination, a. syringe having a plunger, a cylindrical body and a hollow needle with its inner end projecting into the space within the body and its outer end projecting beyond the body, and a discardable cartridge adapted to be received within said body and when so received to constitute the cylinder and piston of the syringe, said cartridge consisting of a tube adapted to contain a. solventl or carrier for a medicament, a hanged, non-metallic plug adapted to close one end of the tube and provided with an axial chamber open to the inside of the tube and adapted to contain said medica.- ment, a closure sealed in the open side of said chamber, said closure being in position to be displaced by the inwardly projecting end of the needle as a necessary result of the act of loading the cartridge into the syringe body and thereby to combine the medicament and carrier, the opposite end of the tube being closed by an unanged plug adapted to be displaced by the inward movement of the plunger and thereby to act as a piston for ejecting ythe mixture within the tube through the needle.

2. A hypodermic injection device, comprising in combination, a syringe having a plunger, a barrel and a hypodermio needle, the parts being adapted to be operated to present an open upper end of the barrel, said needle being positioned with its inner end projecting into the barrel and its outer end projecting beyond the barrel, and a cartridge adapted to be received Within .the open end of the barrel and when so received to constiute the cylinder and piston of the syringe, said cartridge consisting of al tube of substantially uniform diameter from end to end and adapted to contain a carrier for diluent or a medicament, a hanged non-metallic plug adapted to close one end of the tube and provided with a chamber one side of which is open to the inside of the tube, said chamber being adapted to contain said medicament, a closure sealed in the open side of said chamber, said closure beingadapted to be displaced bythe inwardly projecting end of the needle as a result of the placing of the cartridge in operative position in the barrel of the syringe whereby said i chamber is opened and the medicament is permitted to intermix with the diluent, the opposite end of the tube being closed byan uniianged plug adapted to be displaced by the plunger and thereby to act as a. piston for ejecting .the mixture within the tube through the needle.

3. A cartridge for use in hypodermic syringes. consisting oil a tube of. substantially uniform diameter from end to end, a flanged plug composed of rubber or similar material for closing one end of the tube, said plug having a chamber therein with an open side, said opening being of substantially the cross sectional area of the chamber, a disc adapted to be sealed in position to close said opening and when displaced by.a needle projected .through the rubber outer wall of the plug to permit a rapid discharge of the contents of the chamber' into the tube, and an unflanged plug on the opposite end of lthe tube, said plug being adapted to act as a piston to effect the discharge of the contents of the tube through the outlet provided by the said needle.

A4. The combination with a syringe including a cylindrical body, a. plunger, and a hollow needle having its inner end projecting into the space within the body and its outer end projecting beyond the body, of a discardable cartridge adapted to be received within said body and when so received to constitute the cylinder and piston of the syringe, said, cartridge comprising a tube adapted to contain a solvent or carrier for a medicament, a non-metallic plug adapted to close one end of the tube and provided with an axial chamber open to the inside of the tube and adapted to contain said medicament, a disc overlying the inner face of the non-metal1ic plug and sealed thereto over a relatively small area for closing the axial chamber but adapted to be readily displaced therefrom by engagement oi the inwardly projecting end of the needle as a necessary result of the act of loading the cartridge into the syringe body and thereby to combine the medicament and carrier or solvent, the opposite end of the tube being closed by a plug adapted to be displaced by inward movement of ythe plunger and thereby to act as a piston for ejecting the mixture within the tube through the needle.

5. A hypodermie syringe comprising a barrel having a hypodermic needle mounted at one end and extending into the barrel, a plunger mounted at the other end, a discardable cartridge adapted to be received in said barrel through said plunger end, said cartridge comprising a tube having an imperforate plug at one end adapted to be piercedby said needle and a piston plug at the other end adapted to be operated by said plunger, said plugs dening a chamber adapted to hold liquid, said imperforate plug having an axial chamber open to the first chamber and adapted to contain medicament, a closure sealing the open end of said axial chamber and adapted to be displaced by the inwardly extending end of the needle as a necessary act of seating the cartridgeI in the barrel, thereby to combine the medicament and liquid.

CLOYD C. DICKINSON. CLAYTON F. B. STOWELL.

CERTIFICATE OF CORREO TI ON.

cLoYD c. 'DICKINSOIL ET AL.

Itis hereby certified that the above numbered patent was erroneously issued to Cloyd C. Dickinson and Clayton F.' B. Stowell, as assignors, by direct and mesne assignments, to Frankl C. McCrum, whereas said patent should have been issued to Cloyd C. Dickinson and Clayton F. B. S'Lowell, said Stowell n ssignor by mesneassignments of his entire right to Frank -C. HcCI'umhof Chicago, Illinois, as shown by the :recordv of assignments in this office; and that the said Letters Patent shouldbe rend with this correction therein that the same may confonnto the record of' the cese in che Patent office.

signed and sealed this 1st day of July, A.4 D; 19in.

g Henry Van Arsdale, (Seal) 'Acting Conmissioner of Patents. 

